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- What doctors have diagnosed: a layered list of infections and conditions
- How each condition affects the body and the treatment challenges
- Planned operations and an intensive course of IV therapy
- Personal toll: candid posts, ultrasound footage, and financial strain
- How she’s asking the public to respond and what she’s shared about recovery
- Timeline of recent developments and next steps for care
Brandi Glanville announced a major escalation in her long-running health struggle, revealing a cluster of serious diagnoses and an impending surgery to remove a fungal mass in her face. The former Real Housewives star posted a raw video compilation and updates on social media as she prepares for months of intensive treatment.
What doctors have diagnosed: a layered list of infections and conditions
Glanville said medical teams identified multiple problems after years of unexplained facial symptoms. The key findings include:
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- ESBL-producing Klebsiella and Enterobacter with biofilm formation.
- Coccidioidomycosis, commonly called Valley Fever.
- Demodex dermatitis, linked to facial mites.
- Mononucleosis, caused by the Epstein-Barr virus.
- A fungal ball inside facial tissue that needs surgical removal.
She has also been told to remove metals from old dental work and to have her breast implants explanted as part of the overall treatment plan.
How each condition affects the body and the treatment challenges
Antibiotic-resistant bacteria with biofilm
ESBL strains of Klebsiella and Enterobacter produce enzymes that break down many antibiotics. Biofilms allow bacteria to hide in protective layers.

- This combination makes infections harder to eradicate.
- Doctors often need prolonged, targeted IV antibiotics.
- Biofilms can form on implants, teeth, and damaged tissue.
Valley Fever — a fungal lung infection with wider effects
Coccidioidomycosis begins in the lungs after inhaling fungal spores from soil. In some patients, it spreads beyond the lungs.
- Symptoms include fatigue, cough, fever, and sometimes persistent pain.
- Severe or disseminated cases require antifungal therapy and monitoring.
Demodex dermatitis and facial mites
Demodex mites live in hair follicles. When they multiply excessively, especially in people with weakened immune responses, they can inflame the skin.
- Signs include itching, redness, and pimple-like lesions.
- Treatment may involve topical or oral therapies and skin care changes.
Mononucleosis (EBV) and systemic fatigue
Epstein-Barr virus can cause prolonged fatigue, sore throat, swollen lymph nodes, and rashes. It weakens the immune system while active.
- EBV complicates recovery from other infections.
- Supportive care and rest are mainstays while the virus runs its course.
Planned operations and an intensive course of IV therapy
Glanville outlined a demanding regimen ahead. Her doctors plan surgical removal of the fungal mass in the face and the extraction of metal dental work. She will also have her breast implants removed.

She expects 4–6 months of daily IV treatment. The regimen is already taking a toll.
- Daily infusions have lasted up to 18 hours a day, she says.
- Early results show limited improvement, according to her updates.
- Estimated monthly costs range from $3,300 to $6,000.
Glanville added she cannot work much while undergoing treatment, with only her podcast providing income at present.
Personal toll: candid posts, ultrasound footage, and financial strain
She shared video clips showing the physical impact of her illness. Those images include swelling and changes to facial shape that she called some of her worst moments.
The medical team recorded an ultrasound that, Glanville said, detected movement inside the affected facial area. That clip intensified public concern and stirred debate about parasites versus fungal or bacterial causes.
- She previously suspected a parasite migrating across her face.
- She reported spending six figures chasing answers before recent diagnoses.
- In June, clinicians identified a benign facial tumor after extensive testing.
How she’s asking the public to respond and what she’s shared about recovery
Glanville urged followers to be kind in the comments as she posts unflinching footage of illness. She emphasized the reality of how being sick looks and how draining treatment has been.
- She requested empathy while acknowledging her own vulnerability.
- Her posts aim to document the journey and to alert others to complex diagnostic pathways.
- Her care team continues to refine treatment as tests return and surgeries are scheduled.
Timeline of recent developments and next steps for care
- Earlier this year, she first spoke publicly about facial disfigurement and suspected causes.
- Months of specialists, scans, and procedures followed.
- In recent weeks, a combination of lab results and imaging led to the current multi-pronged plan.
- She has upcoming surgeries and a prolonged IV schedule to try to clear the infections.












